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NGS DNA Clean-up & Size Selection 

Product Highlights 

 

CleaniBeads

are magnetic particles for

  • Purifying PCR Amplicons/DNA >100bp

  • Removing salts, enzymes, primers, primer dimers, dNTPs, and contaminants

  • A cost-effective alternative to AMPure XP beads 

 

 

Yielding High-quality DNA

for downstream applications

  • Library clean up for Next-generation sequencing

  • DNA clean up after enzymatic reactions

  • DNA enrichment

  • PCR clean up

  • Cloning 

QC

QC for each lot

Cost-saving

Customized product size on request

Time-saving

~15 mins quick processing time

No Need

centrifugation

FEATURES

 

1

High Recovery with Cleanibeads

Lane 1:

  Pre-purified DNA ladder

 

Lane 2:

  Post-purified DNA ladder using      AMPureⓇ XP (volume ratio 1.8x)

Lane 3:

  Post-purified DNA ladder using

  CleaniBead (volume ratio 1.8x)

Lane 1:

ctDNA NGS library purified with CleaniBead 

(volume ratio 1.8x). The expected library is 200 to 400 bp

Lane 2:

ctDNA NGS library purified with AMPureⓇ XP 

(volume ratio 1.8x)

2

Cleanibeads-to-DNA volume ratio determines the size of purified DNA

Lane 1:

  DNA ladder

 

Lane 2:

  Beads-to-DNA volume ratio = 1.8x

 

Lane 3:

  Beads-to-DNA volume ratio = 1.5x

 

Lane 4:

  Beads-to-DNA volume ratio = 1.2x

Lane 5:

  Beads-to-DNA volume ratio = 0.9x

3

Size selection  ​

to remove unwanted small and large DNA 

(no gel purification needed)

Lane 1:

  Pre-purified DNA ladder

 

Lane 2: 

Post-purified DNA ladder using  CleaniBeads. Large unwanted  DNA was first removed using beads at 0.9x beads-to-DNA volume ratio, followed by the removal of small DNA at 0.2x volume ratio.

 

HOW IT WORKS

Download

 Protocol

 

Ordering

 

*We can tailor-make the product size on your request

*0.5 ml free sample upon request

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Specialized in Liquid Biopsy Testing

Supporting you with Cost-effective Solutions

 

Resources

Protocol

QC data

Lot 0821001

Lot 0821002 

Publication

Unit 625, 6/F Biotech Centre 2, No. 11 Science Park West Avenue, Hong Kong Science Park, NT, Hong Kong

Phone: +852 3188-9335 | Email: support@oncoseek-hk.com

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